SrasV1, Main, Exploration, bibRecord, 005F26

Molecular phylogeny of coronaviruses including human SARS-CoV.

Identifieur interne : 005F26 ( Main/Exploration ); précédent : 005F25; suivant : 005F27

Molecular phylogeny of coronaviruses including human SARS-CoV.

Auteurs : Lei Gao [République populaire de Chine] ; Ji Qi [République populaire de Chine] ; Haibin Wei [République populaire de Chine] ; Yigang Sun [République populaire de Chine] ; Bailin Hao [République populaire de Chine]

Source :

Chinese science bulletin = Kexue tongbao [ 1001-6538 ] ; 2003.

RBID : pubmed:32214701

Abstract

Phylogenetic tree of coronaviruses (CoVs) including the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K-string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus genomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV.

DOI: 10.1007/BF03183929
PubMed: 32214701

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Phylogenetic tree of coronaviruses (CoVs) including the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K-string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus genomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV.</div>
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Molecular phylogeny of coronaviruses including human SARS-CoV.

Molecular phylogeny of coronaviruses including human SARS-CoV.

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Abstract

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